What was the specific original intent of the intervention or procedure described in each of the papers and what was their unintended consequence(s)?Explain

1. What was the specific original intent of the intervention or procedure described in each of the papers and what was their unintended consequence(s)?

2. Can you offer a solution or remediation for any or all of the resulting consequences from these interventions?

3 .What is the Hygiene Hypothesis (described in the Roduit paper) and how is it related to this discussion?

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