Discuss disorders of mineral ion metabolism due to alterations in CaSR expression and/or function

Description

 

– Understand how extracellular free ionised Ca2+ concentration is monitored, and the relative contributions of the parathyroid and kidney calcium-sensing receptor, CaSR

– Discuss disorders of mineral ion metabolism due to alterations in CaSR expression and/or function

– Discuss the discovery of positive allosteric modulators of the CaSR

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