Explain how cardiac ion channelopathies can alter the action potential profile in cardiac cells and the electrical behaviour of the heart.

 

Define the term channelopathy

Explain how cardiac ion channelopathies can alter the action potential profile

in cardiac cells and the electrical behaviour of the heart

 

Discuss the physiology and pathophysiology of potassium ion channels in the

heart, with particular focus on the impact of defective biophysical behaviour

and/or altered trafficking of proteins to the cell membrane

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