If you were tasked with creating a first generation vaccine against an extracellular pathogen, which vaccine development technology would you utilize and why?Explain

What is considered by many to be the “home run” in vaccinology? (2 pts)

What is a T cell-dependent (TD) and T cell-independent (TI) antigen? Why are vaccinologists concerned with TI and TD antigens? How can one overcome any shortcoming in this type of antigen? (3 pts)

If you were tasked with creating a first generation vaccine against an extracellular pathogen, which vaccine development technology would you utilize and why? (2 pts)

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