Cellular and molecular pathology
Refer/Defer Coursework Semester.
The refer/defer assessment for this module is based on the case studies that you studied on your module running in the Semester in which you were enrolled. You will submit a 3000-word report consisting of two parts, vSP4 Part 1 Histopathology Case Study Report and vSP4 Part 2 Haematopathology Case Study Report. Both parts are equally weighted.
Refer to the relevant supporting information and recordings that are in Westminster Slidebox, and the Learning Resources, Assessment, and Panopto (or Collaborate) tabs in Blackboard.
vSP4 Part 1 (50% of the Coursework Marks)
Study the WSIs of the HE-stained sections. Using accurately labelled images to support your work, describe the histopathology of the primary tumour and the liver core biopsy. You should support your description with no more than 4 images. The figure legends will count towards the word limit. (25%, 375 words*)
Using your case as an example, discuss the histopathological investigation of the sentinel lymph node. (25%, 375 words*)
With reference to all of the evidence available to you, provide an illustrated description of the patterns of immunohistochemical staining visible with the different antibodies and discuss how these results will inform the pathologist’s report. You should support your description with no more than 8 images. The figure legends will count towards the word limit. (50%, 750 words*)
vSP4 Part 2 (50% of the Coursework Marks)
Using examples, evaluate how genetic alterations contribute to the development of the haematological malignancy presented in your case. (20%, 300 words*)
Explain why morphological examination was necessary to investigate the patient and compare the value of this technique with ONE other diagnostic method performed in your case study. (40%, 600 words*)
Discuss how targeted drugs provide new opportunities for the treatment of haematological malignancies. You should provide one example relevant to your case and briefly describe how response to treatment may be monitored. (40%, 600 words*)
*The %/words values refer to the suggested distribution of time for Part 1, not marks.
Referencing your Report
The report must be referenced appropriately and consistently in Westminster Harvard format and using a single bibliographic and/or reference list. The bibliography and/or reference list will not contribute to the word count. Do not cite URLs unless this is the only means of accessing the information (e.g. a website or ePublication).
Document format, preparation and submission.
Parts 1 and 2 of vSP4 are to be submitted as one document.
The document should be prepared as a word document, using 2 cm page margins, Arial 12 font and 1.5 line spacing. The document should include a title page, a list of contents, a list of tables and a list of figures, and a table of abbreviations. These are not to be included in your word count. At the end of your document, and before the reference list, you should state you word count.
The final document should be submitted as an uncompressed PDF to avoid disruption of your formatting. Make sure that your file size is less than 100 MB. Please see the coursework submission guidance in the Student Hub for more information on managing file sizes. Do not leave submission of large files to the last minute. They may be queued and end up being marked as late even if submitted before the deadline.
Naming your file
The coursework portfolio must be submitted to Turnitin as a file named as follows:
your student number_6BIOM002W
Failure to follow this instruction may result in your submission not being marked.
Submitting your file
You should submit your work through the Turnitin portal under the tab in Bb.
