Describe how changes in the processes might impact the patient’s recommended drug therapy. Be specific and provide examples.

USE AS REFFERENCES-at least 2

The following guidelines will be helpful for this week:

JNC 8 Guidelines for the treatment of hypertension in adults
ACC/AHA national cholesterol treatment guidelines
ACC/AHA/AATS/PCNA/SCAI/STS Focused Update of the Guideline for Diagnosis and Management of Patients with Stable Ischemic Heart Disease, and
the ACCF/AHA Guideline for the Management of Heart Failure

These disorders are ubiquitous and the pharmacological principles that direct their treatment can be extremely valuable in any capacity as an APN.

The Case Study for this week’s paper is the below. The instructions will ask you to discuss patient factors such as behavior, age, and ethnicity. Since these factors are not provided, you can create your own and discuss how they would affect this patient’s clinical picture and treatment.

Patient AO has a history of obesity and has recently gained 9 pounds. The patient has been diagnosed with hypertension and hyperlipidemia.

Drugs currently prescribed include the following:

Atenolol 12.5 mg daily
Doxazosin 8 mg daily
Hydralazine 10 mg qid
Sertraline 25 mg daily
Simvastatin 80 mg daily

1.Explain how the factor you selected might influence the pharmacokinetic and pharmacodynamic processes in the patient from the case study you were assigned.

2. Describe how changes in the processes might impact the patient’s recommended drug therapy. Be specific and provide examples.

3. Explain how you might improve the patient’s drug therapy plan, and explain why you would make these recommended improvements.

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