Discuss what type of cellular alteration the patient with necrotic toe is likely experiencing. Does this represent an adaptive change, an injury, an irreversible change? Discuss the underlying pathophysiology at the cellular and tissue level. What signs and symptoms would you expect the patient exhibit?

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Discuss what type of cellular alteration the patient with necrotic toe is likely experiencing. Does this represent an adaptive change, an injury, an irreversible change? Discuss the underlying pathophysiology at the cellular and tissue level. What signs and symptoms would you expect the patient exhibit?

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