Critically appraise the diagnosis of Crohn’s and Ulcerative Colitis. Relate the pathogenesis of the disease to the diagnostic techniques that can be used to differentiate between the two conditions.

You need to choose a disease and critically appraise the role of molecular pathology in the prognosis of cancer.

Critically appraise how IHC adds to patient management beyond the information provided by H&E staining.

Use examples of how patient treatment can be directed by IHC tests – consider the limitations of staging and grading.

How can IHC tests add extra information that benefits patients?

.Critical Evaluation

Critically appraise the diagnosis of Crohn’s and Ulcerative Colitis. Relate the pathogenesis of the disease to the diagnostic techniques that can be used to differentiate between the two conditions.

.Minimum word 1800 , maximum 2200.

. Include appropriate tables and diagrams, preferably original images. Diagrams must be have figure legends.

. Everything must referenced from the journal articles using harvard style. In text citation must be used.

.K1. Describe the normal histology of various cells and tissues

K2. Describe the normal cytology of cells as seen in various samples

K3. Describe the appearance of cells and tissues in various pathological processes

K4. Critically discuss the techniques used in the investigation of Cellular Pathology

K5. Critically appraise the use of Cellular Pathology in the diagnosis of cancer

K6. Critically discuss the techniques used in the investigation of cancer

S1. Apply scientific principles and methodologies to the investigation of histo- pathological problems

S2. Analyse, interpret, and critically evaluate scientific knowledge and data

S3. Communicate scientific data effectively, in a variety of reporting styles

S4. Use laboratory and information technology resources competently

S5. Use literature sources effectively

S6. Work independently, and also understand the value of working as part of

a team.