Ventilation-perfusion mismatch. Explain in your own words, the importance/relevance ofthe parameter r V/Q (the ventilation-perfusion ratio) in pulmonary function.

QUESTIONS:

1. ) Solubility of oxygen in the blood. Anemia is a medical condition that develops when the does not
prüce either enough red blood cells or hemoglobin to transfer oxygen to cells at the levels

A) Plot the solubility function — H(Poxygen) for Hill cæffcients of l, 2, and 3, given Pso = 25 mmHg and 8.4 mM. From this information, estimate the hemoglobin content of a red cell in a healthy human.

B) Plot C H(P) for a normal (as above), slightly anemic (20% loss in red cells), and
severely anemic patient (50% loss in red cells) for a Hill coemcient of 3.

C) Interpret the result of your plot with regards to the effæt of anemia on oxygen in the

2. Ventilation-perfusion mismatch. Explain in your own words, the importance/relevance ofthe parameter r V/Q (the ventilation-perfusion ratio) in pulmonary function. In your description, highlight the importance Of r as a mathematical parameter in our mass transport models, as well as its important in both and clinical pulmonary and pathologies..

For question 1 you need to show how you got to answer, I need to see the steps not just graphs, and the numbers they used to plot need to be in the answer too.

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