Describe the concepts leading to the surface plots shown in Figure 2 and supplemental Fig S2.Introduce the function of the Lac operon regulatory network.

Diversity in Lac operon regulation among Escherichia coli isolates

Directions
Main source for this paper should be from the The Sources mentioned below
1. Phillips et al. and 2. Setty el al. The content and goal listed below must be addressed.

Writing doesn’t have to follow traditional essay writing style need to be Content Focused

Background reading if need on lac operon regulation
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Outside reading/ sources not necessary.
Essay must not focus on the writing style but must focus on Content.

Paper Topic: Diversity in Lac operon regulation among Escherichia coli isolates

Essay : Diversity in Lac operon regulation among Escherichia coli isolates.

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Writing essay
Title: Diversity in Lac operon regulation among Escherichia coli isolates.
Sources:
1.  Phillips KN, Widmann S, Lai H-Y, Nguyen J, Ray JCJ, Balázsi G, Cooper TF. 2019. Diversity in lac operon regulation among diverse Escherichia coli isolates depends on the broader genetic background but is not explained by genetic relatedness. mBio10:e02232-19. https://doi.org/10.1128/mBio.02232-19.
2. Setty et al. Detailed map of a cis regulatory function. PNAS 2003.

Goal: Describe the concepts leading to the surface plots shown in Figure 2 and supplemental Fig S2.

Contents MUST include these points below:
1. Introduce the function of the Lac operon regulatory network
2. Describe the experimental methods used by Phillips et al. to obtain the data in
Figure 2
3.     Discuss the deterministic model used by Phillips et al.

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