Digoxin is a drug which undergoes little metabolism and is mainly eliminated through renal excretion. What would happen to the plasma levels of digoxin in a patient with renal impairment?Explain

What is pharmacokinetics?

List and briefly describe the processes involved in pharmacokinetics?

What is pharmacodynamics

Identify the 4 common modes of actions of drugs.

What is the meaning of the word agonist and antagonist?

Watch the following video on first pass metabolism or effect and answer the questions below

https://www.youtube.com/watch?v=BQQns7RAUzA.

What happens to the drug in the liver?

What is meant by drug bioavailability?

What is the first pass effect?

Will a drug that undergoes extensive first pass metabolism have low or high bioavailability? Why?

Digoxin is a drug which undergoes little metabolism and is mainly eliminated through renal excretion. What would happen to the plasma levels of digoxin in a patient with renal impairment?

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