What factors may have contributed to the development of PUD? How do these factors contribute to the formation of peptic ulcers? 

A 45-year-old male comes to the clinic with a chief complaint of epigastric abdominal pain that has persisted for 2 weeks. He describes the pain as burning, non-radiating and is worse after meals. He denies nausea, vomiting, weight loss or obvious bleeding. He admits to bloating and frequent belching.

PMH-+ for osteoarthritis, seasonal allergies with frequent sinusitis infections.

Meds-Zyrtec 10 mg po daily and takes it year-round, ibuprofen 400-600 mg po prn pain

Family Hx-non contributary

Social history-recently divorced and expressed concern at how expensive it is to support 2 homes. Works as a manager at a local tire and auto company. He has 25 pack/year history of smoking, drinks 2-3 beers/day, and drinks 5-6 cups of coffee per day. He denies illicit drug use, vaping or unprotected sexual encounters.

Breath test in the office revealed + urease.

The healthcare provider suspects the client has peptic ulcer disease.

1 of 2 Questions:

What factors may have contributed to the development of PUD?
2 of 2 Questions:
How do these factors contribute to the formation of peptic ulcers?

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