Sometimes “Polyene” cyclization reactions can be catalyzed by a transition metal. Provide a mechanism for the reaction.

Provide mechanisms and/or products for the following transformations.

a. Sometimes “Polyene” cyclization reactions can be catalyzed by a transition metal. Provide a mechanism for the reaction.

Section I. Tactics

Provide the appropriate reagents or product in the following examples.

1.
2.
3.
4.
5.
6.
7.

1.OsO4, TBHP, H2O/THF

Br

2. TsOH, acetone, PhH, heat

3. AlCl3, CH3COCl, CH2Cl2

1. BzOOBz, NBS, CCl4

 

2. Mg, THF; then Pd0Ln, PhBr

3. HNO3, H2SO4

4. Zn, HCl

 

1. Pd0Ln, Et3N, MeCN

2. NaBH4, MeOH 3. , Et3N, CH2Cl2 Cl

 

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