Where in the protein might the amino acid substitutions be located? Why would altering protein structure at this site result in the phenotypes that you see illustrated in the figure?
Biochemical Pathways Below are representative transmission electron micrographs (TEM) of the WT and mutant P. gingivalis strains as well as quantitative data that measures the quantity of OMVs produced by these bacterial strains. To generate the graph, please note that the Alaei lab used a fluorescent probe to quantitate the relative levels of OMVs produced […]