Identify and explain the rationale underlying at least three main controls and/or optimisation procedures which are required to reduce false positive and/or false negative results.

Questions: Q1) EpCam (Epithelial cell adhesion molecule) has been associated with several cancers including breast cancer. In the paper by Soysal et al (2013) entitled ‘EpCAM expression varies significantly and is differentially associated with prognosis in the luminal B HER2+, basal-like, and HER2 intrinsic subtypes of breast cancer’ the authors investigated levels of EpCam using […]

Using suitable technical language, describe the histopathology of the primary tumour in your case and discuss how the investigation was supported by the use of immunohistochemistry to suggest that the aberrant tissue morphology seen in the liver arose from the glandular epithelium of the colon.

Immunohistochemistry, Haematopathology and histopathology Overview The Coursework Portfolio is a body of work involving a mix of collaborative and individual tasks based on the practical study of histopathology and haematology cases. You will be working with a variety of tools to produce a range of content that can be reviewed formatively and assessed summatively. These […]

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