Describe in your Synoptic Essay the disease MCAD. Consider in your answer mitochondrial βoxidation of fatty acids in healthy individuals, both at the molecular but also at the organ level, and include how substances are distributed in the entire body via the circulatory system. Describe what changes happen in patients with MCAD disease at molecular, physiological, and anatomical levels.
Disease MCAD Description A 4-year old girl is brought into the A & E Department because she lost consciousness. The girl is hypoglycaemic, with a glucose concentration of 3.6 mmol/L glucose (normal range: 4.0 to 5.4 mmol/L). There is no history of diabetes. However, the parents report that the girl had been suffering from gastroenteritis, […]