Describe the Effect of autophagy on ROS generation in Kras driven NSCLC, and inducing or inhibiting ferroptosis.
Description Lung cancer, statistics, mutations: Kras/Braf/EGFR, LKB1, p53 etc. in non-small cell lung cancer (NSCLC), treatment strategies and current ongoing clinical trials and setbacks. mTOR/MEK/ERK signaling pathway, and autophagy signaling pathway and their upregulation in cancer, specifically lung and pancreatic cancer. Role of autophagy in Kras driven NSCLC and recent studies for using autophagy inhibitors […]